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Peptide Hormone

Search Result - 1

HMRbase accession number	10073
Swiss-prot Accession number	Q8WN12 (Sequence in FASTA format)
Description	Prolactin-releasing peptide precursor (PrRP) (Prolactin-releasinghormone) [Contains: Prolactin-releasing peptide PrRP31; Prolactin-releasing peptide PrRP20].
Source organism	Ovis aries (Sheep)
Taxonomical Classification	Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Cetartiodactyla; Ruminantia;Pecora; Bovidae; Caprinae; Ovis.
Subcellular location	Secreted protein
Developmental Stage	N/A
Similarity	N/A
Tissue Specificity	More abundantly expressed in the brainstem than the hypothalamus
Post translational modification	N/A
Function	Stimulates prolactin (PRL) release and regulates the expression of prolactin through its receptor GPR10. May stimulate lactotrophs directly to secrete PRL
Protein Length	98 Amino acids
Molecular weight	10513
References	1  PubMed abstract 12098662
Domain Name	N/A
Hormone Name	Prolactin-releasing peptide PrRP20
Mature Hormone Sequence	RTPDINPAWYAGRGIRPVGRF
Position of mature hormone in Pre-Hormone protein	21 Residues from position (33-53)
Receptor	N/A
Gene ID	443466
PDB ID	N/A
Drugpedia	wiki
Comments	!Receptor for this Hormone are either unknown or have not yet been curated

Search Result - 2

HMRbase accession number	10304
Swiss-prot Accession number	P81264 (Sequence in FASTA format)
Description	Prolactin-releasing peptide precursor (PrRP) (Prolactin-releasinghormone) [Contains: Prolactin-releasing peptide PrRP31; Prolactin-releasing peptide PrRP20].
Source organism	Bos taurus (Bovine)
Taxonomical Classification	Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Cetartiodactyla; Ruminantia;Pecora; Bovidae; Bovinae; Bos.
Subcellular location	Secreted protein
Developmental Stage	N/A
Similarity	N/A
Tissue Specificity	Medulla oblongata and hypothalamus
Post translational modification	N/A
Function	Stimulates prolactin (PRL) release and regulates the expression of prolactin through its receptor GPR10. May stimulate lactotrophs directly to secrete PRL
Protein Length	98 Amino acids
Molecular weight	10544
References	1  PubMed abstract 9607765
Domain Name	N/A
Hormone Name	Prolactin-releasing peptide PrRP20
Mature Hormone Sequence	RTPDINPAWYAGRGIRPVGRF
Position of mature hormone in Pre-Hormone protein	21 Residues from position (33-53)
Receptor	Q4EW11    Detail in HMRbase
Gene ID	286856
PDB ID	N/A
Drugpedia	wiki
Comments

Search Result - 3

HMRbase accession number	10306
Swiss-prot Accession number	P81277 (Sequence in FASTA format)
Description	Prolactin-releasing peptide precursor (PrRP) (Prolactin-releasinghormone) [Contains: Prolactin-releasing peptide PrRP31; Prolactin-releasing peptide PrRP20].
Source organism	Homo sapiens (Human)
Taxonomical Classification	Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo.
Subcellular location	Secreted protein
Developmental Stage	N/A
Similarity	N/A
Tissue Specificity	Medulla oblongata and hypothalamus
Post translational modification	N/A
Function	Stimulates prolactin (PRL) release and regulates the expression of prolactin through its receptor GPR10. May stimulate lactotrophs directly to secrete PRL
Protein Length	87 Amino acids
Molecular weight	9639
References	1  PubMed abstract 9607765 2  PubMed abstract 15489334 3  PubMed abstract 10498338
Domain Name	N/A
Hormone Name	Prolactin-releasing peptide PrRP20
Mature Hormone Sequence	TPDINPAWYASRGIRPVGRF
Position of mature hormone in Pre-Hormone protein	20 Residues from position (34-53)
Receptor	P49683    Detail in HMRbase
Gene ID	51052
PDB ID	N/A
Drugpedia	wiki
Comments

Search Result - 4

HMRbase accession number	10307
Swiss-prot Accession number	P81278 (Sequence in FASTA format)
Description	Prolactin-releasing peptide precursor (PrRP) (Prolactin-releasinghormone) [Contains: Prolactin-releasing peptide PrRP31; Prolactin-releasing peptide PrRP20].
Source organism	Rattus norvegicus (Rat)
Taxonomical Classification	Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi;Muroidea; Muridae; Murinae; Rattus.
Subcellular location	Secreted protein
Developmental Stage	N/A
Similarity	N/A
Tissue Specificity	Widely expressed, with highest levels in medulla oblongata and hypothalamus
Post translational modification	N/A
Function	Stimulates prolactin (PRL) release and regulates the expression of prolactin through its receptor GPR10. May stimulate lactotrophs directly to secrete PRL
Protein Length	83 Amino acids
Molecular weight	9215
References	1  PubMed abstract 9607765 2  PubMed abstract 11178959 3   Anderson S.T., Kokay I.C., Lang T., Grattan D.R., Curlewis J.D.; "Quantitation of prolactin-releasing peptide (PrRP) mRNA expression inspecific brain regions during the rat oestrous cycle and inlactation."; Submitted (JUN-2002) to the EMBL/GenBank/DDBJ databases. 4  PubMed abstract 10498338
Domain Name	N/A
Hormone Name	Prolactin-releasing peptide PrRP20
Mature Hormone Sequence	TPDINPAWYTGRGIRPVGRF
Position of mature hormone in Pre-Hormone protein	20 Residues from position (33-52)
Receptor	Q64121    Detail in HMRbase
Gene ID	63850
PDB ID	N/A
Drugpedia	wiki
Comments